COVID-19 and seizures: Is there a link. Patients with COVID-19 who have no history of epilepsy may be at risk for novel seizures and subsequent adverse outcomes, including increased mortality. Epilepsy and COVID-19: Risks, vaccination, and safety - Medical News Today More guidelines and information on Disputes & Debates, Prospective Long-term Follow-up of Focused Ultrasound Unilateral Subthalamotomy for Parkinson Disease, Neurology | Print ISSN:0028-3878 Getting sick or having a fever, in general, can make seizures more frequent, however. Most people with epilepsy will stop having seizures after trying just one or two medicines. Epidemiology, pathophysiology, and classification of the neurological symptoms of post-COVID-19 syndrome. Epilepsia. People and clinicians may choose not to initiate medication, even after 2 unprovoked seizures, if these occur proximal to COVID-19 infection and perhaps particularly if EEG and MRI do not suggest an underlying substrate for seizures. Your organization or institution (if applicable), e.g. Syncope, Seizure May Precede Cardiac Arrest in Children, Young Adults . 4 Department of Neurology, University Hospital . Devinsky O., Gazzola D., LaFrance W.C., Jr. Differentiating between non-epileptic and epileptic seizures. Epub 2022 Dec 12. Submitted comments are subject to editing and editor review prior to posting. MRI imaging confirmed chronic small vessel ischemic changes, but no stroke or abnormal patterns of enhancement as depicted by the post contrast fluid attenuated recovery sequence (C). FOIA We assessed established and suspected risk factors for COVID-19 and for more severe COVID-19 illness: age, sex, race, ethnicity, obesity, hypertension, diabetes, chronic kidney disease, asthma, chronic lower respiratory diseases, nicotine dependence, substance misuse, previous psychiatric illness, ischemic heart disease and other forms of heart diseases, socioeconomic deprivation, cancer (and hematologic cancer in particular), chronic liver disease, stroke, dementia, organ transplant, rheumatoid arthritis, lupus, psoriasis, and disorders involving an immune mechanism. Older adults and people with multiple health conditions seem to be at the highest risk of developing seizures related to COVID-19. Five of the people develop generalized tonic-clonic seizures. Overall, 2% of 172,959 adults in the National Survey of Epilepsy, Comorbidities and Health Outcomes self-reported an epilepsy diagnosis. Weve seen that COVID-19 can cause events called cytokine storms where the virus causes the body to over-produce cytokine which can cause damage and inflammation in various organs. COVID-19; Epilepsy; Functional seizures; Pandemic; Psychogenic nonepileptic seizures (PNES); Stress. In addition, we cannot compare postCOVID-19 sequelae with infections with more epileptogenic viruses, such as herpes simplex virus,32 because there are insufficient case numbers. Effect of neurofeedback therapy on neurological post-COVID-19 complications (A pilot study). The .gov means its official. Seizure First Aid Training: Live Webinar June 6th | Epilepsy Foundation Yes, COVID-19 has been known to cause seizures. COVID-19 FAQS for people with epilepsy and carers. There are a few potential ways that the SARS-CoV-2 virus may trigger seizures. Epilepsy Behav. What types of seizures are possible after COVID-19 recovery? Epub 2021 Dec 14. Your email address, e.g. The handling editor was Barbara Jobst, MD, PhD, FAAN. Admittedly, EEG studies have been significantly underused due to exposure . Marijuana use in adults admitted to a Canadian epilepsy monitoring unit. PMC Development of a brain wave model based on the quantitative analysis of EEG and EEG biofeedback therapy in patients with panic attacks during the COVID-19 pandemic. We then explored time-varying HRs to assess temporal patterns of seizure or epilepsy diagnoses. (2022). The https:// ensures that you are connecting to the 2023 Feb;77(2):84-93. doi: 10.1111/pcn.13508. Seizure First Aid Certification: Live Webinar June 6, . The .gov means its official. The baseline demographic data of the cohorts, before and after matching, are presented in Table 1 (and eTable 1, links.lww.com/WNL/C480). HHS Vulnerability Disclosure, Help Possible Mechanisms Underlying Neurological Post-COVID Symptoms and Neurofeedback as a Potential Therapy. National Library of Medicine An increasing HR over time only implies that the incidence in 1 group increases relative to the other group. In a March 2022 study from South Korea, researchers found that 6 out of 1,487 people hospitalized with COVID-19 developed new-onset seizures. Patients with PNES showing symptoms of anxiety and depression are at higher risk of seizure worsening. . I was diagnosed with epilepsy in 2012 after having what I now know to be focal impaired awareness seizures. -, Kandemirli S.G., Dogan L., Sarikaya Z.T. Under these circumstances, seizures could occur with COVID-19 in a person without epilepsy or certain neurological disorders. eCollection 2022. Washington, DC, American Psychiatric Association. Significance: 2020 Oct 28;21(1):897. doi: 10.1186/s13063-020-04819-9. Data presented in this article and the Supplement are freely accessed at osf.io/m8ht2. Hazard ratios (HRs) with 95% CIs were calculated using the Cox model, and the null hypothesis of no difference between cohorts was tested using log-rank tests. Maury A, Lyoubi A, Peiffer-Smadja N, de Broucker T, Meppiel E. Rev Neurol (Paris). Cognitive behavioural therapy for psychogenic nonepileptic seizures Parent/Caregiver Support Group | Epilepsy Foundation ACS Chem. COVID-19 and Epilepsy. Letter to the editor. Professor Arjune Sen, Nuffield Department of Clinical Neurosciences, on new research suggesting that though the overall risk of seizures is small, it is greater after COVID. There are many different options for anti-seizure medicines. . In a May 2022 study using data from the Centers for Disease Control (CDC), researchers estimated that the incidence of seizures following COVID-19 vaccination was 3.19 per 100,000 people per year.They also estimated that the risk was 0.090 per 100,000 people per year for flu vaccines. You must ensure that your Disclosures have been updated within the previous six months. Would you like email updates of new search results? Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19: A structured summary of a study protocol for a randomised controlled trial. You asked, we answered: Can COVID-19 cause seizures? In a large electronic health records network, our study revealed that COVID-19 is associated with an increased risk of seizures or epilepsy when compared with matched patients with influenza over 6-month time horizon from the date of infection. New onset acute symptomatic seizure and risk factors in coronavirus disease 2019: A retrospective multicenter study. Psychiatry Clin Neurosci. But there have also been first-time seizures in people. Encephale. Neurol Perspect. All Rights Reserved. doi: 10.1001/jama.290.5.612. This site needs JavaScript to work properly. Epub 2018 Mar 27. COVID-19 presenting as a seizure: A Kenyan case report. By contrast, severe infections can directly lower seizure threshold owing to metabolic disturbances, fever, sleep deprivation, and other factors. The interictal electroencephalographic (EEG) signal may also be normal in patients with ES. Federal government websites often end in .gov or .mil. You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid Learn more. Taquet M, et al. In people who were hospitalized the risks of seizures and/or epilepsy were similar after COVID-19 and influenza infections. Neurol. The goal of medicine is to find what works best for you and causes the fewest side effects. The .gov means its official. See this image and copyright information in PMC. In those who do start medication, especially children, it will be crucial to track seizure profiles and long-term neurodevelopmental/neurocognitive outcomes. Propensity score matching (performed within the TriNetX network) created cohorts with matched baseline characteristics.15 Propensity score 1:1 matching used a greedy nearest neighbor approach with a caliper distance of 0.1 pooled SDs of the logit of the propensity score. Nouh A., Remke J., Ruland S. Ischemic posterior circulation stroke: a review of anatomy, clinical presentations, diagnosis, and current management. There has been no definitive association between COVID-19 and seizures, and researchers are still investigating the strength of the relationship and the possibility of a chance relationship. There, Radiographic and electrographic data. 2022 Feb;127:108454. doi: 10.1016/j.yebeh.2021.108454. The time of peak HR after infection differed by age and hospitalization status. Epilepsy Behav. Vosburgh S, et al. (Exception: original author replies can include all original authors of the article). HHS Vulnerability Disclosure, Help For further details about TriNetX, see eMethods, links.lww.com/WNL/C480. Psychogenic nonepileptic seizures (PNES) may look like generalized or other forms of epileptic seizures but are caused by brain dysfunction and not by abnormal electrical signaling in the brain. Guidance. -, Rosengard J.L., Donato J., Ferastraoaru V., Zhao D., Molinero I., Boro A., et al. Seizures associated with coronavirus infections - PMC To reduce confounders, groups were then closely matched for demographic characteristics and multiple systemic and psychiatric comorbidities, leading to matched cohorts of individuals diagnosed with COVID-19 and influenza each consisting of 152,754 individuals. Hospitalization status was a significant moderator for the association between COVID-19 and epilepsy (with the association being more marked among nonhospitalized patients; moderation coefficient 0.52, 95% CI 0.110.93, p = 0.012), but not for seizures (moderation coefficient 0.047, 95% CI 0.20 to 0.29, p = 0.70). This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. As we used anonymized routinely collected data, no participant consent was required. 2020;297(1):E232E235. You may have episodes of movement, sensation, and behavior similar to an epileptic seizure and may have a temporary loss of attention or memory lapse. 2022 Aug;219:107310. doi: 10.1016/j.clineuro.2022.107310. To explore whether, and how, associations between COVID-19 and epilepsy or seizures are affected by the severity of the acute infection, we repeated the analysis separately in those who were hospitalized and those not hospitalized within 14 days of their COVID-19 or influenza diagnosis. Pathophysiology of COVID-19: why children fare better than adults? Taking Melatonin: Can You Mix Melatonin and Alcohol? Last medically reviewed on November 4, 2022. Before Neurological events reported after COVID-19 vaccines: An analysis of vaccine adverse event reporting system. We do not endorse non-Cleveland Clinic products or services. Higher scores of GAD-7 items (p < 0.001) and NDDI-E (p < 0.001) were associated with PNES worsening. A new CDC analysis finds that people over 40, women, Black people, and individuals with underlying health conditions are most at risk of long COVID-19. Acute symptomatic seizures have been reported in sporadic cases in patients with COVID-19.1 2 However, a recent large retrospective cohort study suggested that there was no increased risk of acute symptomatic seizures in these patients.3 As such, the association of seizures with COVID-19 has not been established. COVID-19 can have damaging effects on multiple organs in the body, including the brain. This study has several limitations beyond those inherent to research using electronic health records4,31 (summarized in the eMethods, links.lww.com/WNL/C480), such as the unknown completeness of records, no validation of diagnoses, and sparse information on socioeconomic and lifestyle factors. The virus seems to primarily trigger seizures through indirect means, such as increased levels of pro-inflammatory molecules in your brain. Cohorts included all patients who had the index event (COVID-19 or influenza) between January 20, 2020 (the date of the first recorded COVID-19 case in the United States), and May 31, 2021, and who were still alive at the end of follow-up (August 24, 2021). COVID-19 Linked to New-Onset Epileptic Seizures - Medscape However, hospitalization status was not a significant moderator (moderation coefficient 0.12, 95% CI 0.10 to 0.35, p = 0.28). 'MacMoody'. Learn more. -, Baig A.M., Khaleeq A., Ali U., Syeda H. Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms. A national survey of stress reactions after the September 11, 2001, terrorist attacks. Currently, WHO-approved COVID-19 vaccines include RNA, adenovirus vector, and inactivated vaccines. The HR of epilepsy after COVID-19 compared with influenza was greater in people who had not been hospitalized and in individuals younger than 16 years. This site needs JavaScript to work properly. Epub 2019 Aug 2. Results We analyzed 860,934 electronic health records. While seizures and status epilepticus have not been widely reported in the past five months since the onset of COVID-19 pandemic, patients with COVID-19 may have hypoxia, multiorgan failure, and severe metabolic and electrolyte disarrangements; hence, it is plausible to expect clinical or subclinical acute symptomatic seizures to happen in these Increased pediatric functional neurological symptom disorders after the Boston marathon bombings: a case series. Epilepsy Behav. Using the TriNetX user interface, cohorts are created based on inclusion and exclusion criteria, matched for confounding variables, and compared for outcomes of interest over specified periods. Effects of a psychotherapeutic group intervention in patients with refractory mesial temporal lobe epilepsy and comorbid psychogenic nonepileptic seizures: A nonrandomized controlled study. Most investigations of COVID-19 and seizures have focused on the acute setting, whereas assessments of medium-term neurologic outcomes have not included epilepsy or had low case numbers.4,14 We, therefore, examined a large data set of healthcare records to determine the incidence of seizures and epilepsy in the 6 months after COVID-19 infection and compare these risks with matched patients after infection with influenza. 2003;290(5):612620. (2022). This happens with other respiratory infections, too. Epileptic Seizure in Epilepsy Patients After SARS-CoV-2 Vaccination This was compared with a matched cohort of patients diagnosed with influenza (ICD-10 codes J09-J11) who did not have either a diagnosis of COVID-19 or a positive test for COVID-19. Learn more about types of seizures, causes and symptoms, and how you can help someone having, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. The rate of new cases of epilepsy or seizures was 0.94% in the people who had COVID, compared with 0.6% in those who had influenza. In nonhospitalized patients, COVID-19 associated with significantly increased risks of seizures and/or epilepsy. 2021 Dec;1:S5-S15. MHRA advice on antiepileptic drugs . Incidence of Epilepsy and Seizures Over the First 6 Months After a Abstract Importance: The absence of a positive diagnosis of psychogenic non-epileptic seizures (PNES) in immunization stress-related response (ISRR) clusters may have not only a direct impact on affected patients' health but may also reduce compliance to national vaccination programs. (2022). Major finding: About 5% of patients had complications during video-electroencephalographic monitoring, and about 90% of the patients were diagnosed on the basis of the results.Data source: A prospective study of 158 patients admitted during a 5-year period.Disclosures: The study was not funded. Immune-mediated or inflammatory-mediated mechanisms of COVID-19 could contribute to epileptogenesis in the developing brain or unmask a previous predisposition to seizures. Submitted and externally peer reviewed. Dawit S, Okazaki E, Girardo ME, Drazkowski JF. MeSH Policy. Non-epileptic seizures and dissociative seizures - Epilepsy Society Brain MRI findings in patients in the intensive care unit with COVID-19 infection. Bookshelf It will be important to monitor these individuals to determine whether further seizures supervene. Acute stress disorder; Anxiety; COVID-19; Depression; Functional seizures; Psychogenic nonepileptic seizures. Kopaska M, Ochojska D, Mytych W, Lis MW, Bana-Zbczyk A. Sci Rep. 2022 Sep 1;12(1):14908. doi: 10.1038/s41598-022-19068-w. PLoS One. Compared with influenza, COVID-19 associates with an increased probability of being diagnosed with seizures and/or epilepsy in both age groups. Children with neurologic manifestations can be more likely to have positive COVID-19 antibodies either alone or in combination with COVID-19 PCR positivity. (2020). Describing dissociative seizures. Submit only on articles published within 6 months of issue date. COVID-19 and Seizures | Epilepsy Foundation Neurologic deficits are often an important presenting symptom. A few patients, particularly those with prior neurological issues, may experience occasional seizures. The risk of neurological complications after COVID-19 infection is up to 617 times higher than after COVID-19 vaccination. Accessibility That the varying time of peak risk related to hospitalization and age may provide clues as to the underlying mechanisms of COVID-associated seizures and epilepsy. The incidence of acute symptomatic seizures with COVID-19 infection (1%) is lower than with SARS (2.7%) and Middle East Respiratory Syndrome (8.6%).13 Given the heterogeneous literature, it remains uncertain if COVID-19 infection predisposes patients to develop seizures or epilepsy. 2018 May;58:22-28. doi: 10.1016/j.seizure.2018.03.023. Ghadimi K, Heidari Z, Kheradmand M, Najafi MA, Chitsaz A, Khorvash F, Fahim M, Najafi MR. Am J Neurodegener Dis. The differential diagnosis of epileptic seizures (ES) and psychogenic non-epileptic seizures (PNES) may be difficult, due to the lack of distinctive clinical features. Seizures seem to be most common in people with severe COVID-19 and in older adults. The site is secure. Front Hum Neurosci. Compared with influenza, there was a significantly increased risk of the composite endpoint of seizures or epilepsy after COVID-19 in nonhospitalized individuals (0.72% vs 0.48%, HR 1.44, 95% CI 1.271.63, p < 0.0001) but not in hospitalized individuals (2.90% vs 2.40%, HR 1.14, 95% CI 0.951.38, p = 0.16). Courage to Cross the Finish Line | eJourney - epilepsy.com One primary way the virus may trigger these seizures is related to how the virus enters the nervous system. Radiographic and electrographic data. Neurological Events Reported after COVID-19 Vaccines: An Analysis of VAERS. Clin Neurol Neurosurg. Similarly, there were significantly increased risks in both seizures and epilepsy measured individually in the nonhospitalized group only (Figure 3). Management of Psychogenic Nonepileptic Seizures Your role and/or occupation, e.g. Medical management of epilepsy seeks to eliminate or to reduce the frequency of seizures, help patients maintain a normal lifestyle, and maintain psychosocial and occupational activities, while avoiding the negative side effects of long-term treatment. 2011;7:210220. Its a good idea to see a doctor if you have lingering symptoms for 4 weeks or more. Reference 1 must be the article on which you are commenting. [Psychogenic non epileptic seizures: a review]. Epub 2021 Feb 12. 2001;345(20):15071512. ), University of Oxford, UK; Oxford Health NHS Foundation Trust (M.T., P.J.H. The results for the analysis stratified by age between children (aged 16 years, n = 43,231 after matching; see eTable 2, links.lww.com/WNL/C480 for baseline characteristics) and adults (aged >16 years, n = 108,116 after matching; eTable 3, links.lww.com/WNL/C480) are summarized in Figure 2 and Table 3. Non-epileptic myoclonus status can be due to both SARS-CoV-2 infection The effects of this inflammation on the brain could explain these seizures. Ludvigsson JF, et al. COVID-19 associates with psychological comorbidity, both in those with preexisting seizures33,-,35 and in those who do not have epilepsy.4 Although psychological stresses can contribute to the development of epilepsy, this can also precipitate psychological nonepileptic attacks (PNES, dissociative seizures, and functional seizures).36 PNES may be miscategorized as seizures or epilepsy, and this may be overrepresented in the COVID-19 cohort. Clipboard, Search History, and several other advanced features are temporarily unavailable. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. 8600 Rockville Pike COVID-19 and Seizures. Lu L, et al. Staying Safe During the COVID-19 Crisis. These are called 'psychogenic nonepileptic seizures' or PNES for short. sharing sensitive information, make sure youre on a federal ncbi.nlm.nih.gov/pmc/articles/PMC7373049/, ncbi.nlm.nih.gov/pmc/articles/PMC7212943/, bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.15415, journals.lww.com/jfmpc/Fulltext/2021/10070/Seizure_after_recovery_from_Covid_19.46.aspx?WT.mc_id=HPxADx20100319xMP, ncbi.nlm.nih.gov/pmc/articles/PMC8960940/, ilae.org/patient-care/covid-19-and-epilepsy/for-patients/faqs-in-english, onlinelibrary.wiley.com/doi/10.1002/ana.26339, cureus.com/articles/110322-covid-19-induced-seizures-a-meta-analysis-of-case-series-and-retrospective-cohorts, ncbi.nlm.nih.gov/pmc/articles/PMC8397499/, nhs.uk/conditions/coronavirus-covid-19/long-term-effects-of-coronavirus-long-covid/, onlinelibrary.wiley.com/doi/10.1111/apa.16276, onlinelibrary.wiley.com/doi/10.1111/epi.16524, cureus.com/articles/76736-covid-19-presenting-as-a-seizure-a-kenyan-case-report, n.neurology.org/content/98/18_Supplement/1689, thelancet.com/journals/lanpsy/article/PIIS2215-0366(22)00260-7/fulltext, onlinelibrary.wiley.com/doi/10.1111/epi.16656, epilepsy.com/complications-risks/moods-behavior/stress-mood-and-seizures, sciencedirect.com/science/article/pii/S1059131122001583, Long COVID: The Latest on Risks, Recovery, and Treatment, These Groups Are at Higher Risk of Developing Long COVID-19. All rights reserved. The incidence of influenza has decreased during the COVID-19 pandemic, so those affected might not be representative of people diagnosed with influenza before the pandemic. According to the International League Against Epilepsy, research suggests that theres a low risk of seizures getting worse for most people with epilepsy. Epub 2022 May 11. Psychogenic non-epileptic seizures (PNES) in the COVID-19 pandemic era: A systematic review with individual patients' analysis. Would you like email updates of new search results? One primary way the virus may trigger these seizures is related to how the virus enters the nervous system. We sought to determine whether an underlying cause of seizures could be identified, particularly considering if stroke, a potential consequence of COVID-19,28,-,30 may be the main cause of COVID-19related seizures or epilepsy. Of the 859 patients, 217 (25.3%) had various non-epileptic adverse events, and none had severe non-epileptic adverse events. Those without neurologic manifestations often only had positive COVID-19 PCR results, suggestive of acute infection.20. 2014;5:30. 2023 Epilepsy Foundation, is a non-profit organization with a 501(c)(3) tax-exempt status. VAERS-reported new-onset seizures following use of COVID-19 - PubMed 2020 Jun 3;21(1):466. doi: 10.1186/s13063-020-04436-6. COVID-19 and Seizures. The comparison cohort was selected to be contemporaneous to the COVID-19 cohort to limit the effect of contextual factors (e.g., strained health services) on outcomes. Epilepsy has neurodevelopmental, psychological, social, and educational consequences.25,26 Although the infection is often mild in children, neurologic consequences of COVID-19 may potentially be more severe.27 Our data provide additional support for preventing COVID-19 infection in children, which can inform the risks-benefits balance of vaccination in pediatric populations. Like in any illness, when someone with epilepsy gets sick or dehydrated, that can provoke a seizure. Please enable it to take advantage of the complete set of features! However, in an August 2022 study, researchers found that among 1.3 million people who had COVID-19, the risk of seizures, brain fog, dementia, and psychotic disorders was still increased 2 years later. In nonhospitalized patients, COVID-19 associated with significantly increased risks of seizures and/or epilepsy. Any characteristic with a standardized mean difference between cohorts lower than 0.1 is considered well matched.16 The Kaplan-Meier estimator was used to estimate the incidence of each outcome. -. A Reporting of studies Conducted using Observational Routinely collected health Data (RECORD) statement was completed. A new study led by investigators at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) indicates that some hospitalized patients with COVID-19 experience nonconvulsive seizures, which may put them at a higher risk of dying. JAMA Neurol. The COVID-19 outbreak and PNES: The impact of a ubiquitously felt stressor. PMC The relative risk is, though, greater after COVID-19 infection than after influenza, particularly in people who were not hospitalized and in children (aged less than 16 years). An overview of machine learning methods in enab (retired), The Significance of the Increased Incidence of New Onset Seizures and Epilepsy After a COVID-19 Infection, Creative Commons Attribution License 4.0 (CC BY), Neurology: Neuroimmunology & Neuroinflammation. Careers. official website and that any information you provide is encrypted The proportional hazard assumption was tested using the generalized Schoenfeld approach. COVID-19 has also been linked to febrile seizures, which are seizures in children triggered by high fevers. ), UK; Department of Neurology (O.D. Biomedicines. The work was supported by the National Institute for Health and Care Research (NIHR) Oxford Health Biomedical Research Centre (BRC), Grant No. At the very end stages of serious forms of COVID-19, damage to other organs can happen, including damage to the brain. Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Seizures are not a symptom of COVID-19. Copyright 2021 Elsevier Inc. All rights reserved. Epilepsy Behav. The site is secure. Seizures have been observed in COVID-19 patients who dont have epilepsy but why that happens is still not fully clear. The peak HR in these more susceptible groups occurred some weeks after infection with COVID-19, potentially suggesting an immune-mediated etiology. If the assumption was violated, a time-varying HR was estimated using natural cubic splines fitted to the log-cumulative hazard.17. Unauthorized use of these marks is strictly prohibited. The incidence of new-onset seizures, which we defined as de novo seizures occurring within 4 weeks of receiving any of the US Food and Drug Administration-approved COVID-19 vaccinations as reported in patient-reported data compiled in the US Centers for Disease Control and Prevention Vaccine Adverse Events Reporting System Data (CDC VAERS), has . Does not increase the risk of getting COVID-19 AND Does not increase the severity of COVID-19 There is no evidence that people with epilepsy alone have a weakened immune system. A nonepileptic seizure does not involve abnormal brain activity. Baseline Characteristics for COVID-19 and Influenza Cohorts Before and After Matching. Wang C., Pan R., Wan X., Tan Y., Xu L., Ho C.S., et al. Focal onset non-motor seizure following COVID-19 vaccination - PubMed We read with interest the article by Ben Mohamed et al. A first case of meningitis/encephalitis associated with SARS-Coronavirus 2.

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